Pedunculopontine nucleus DBS for Parkinson’s disease

Pedunculopontine nucleus DBS is a promising new treatment for gait freezing and postural instability (poor balance) in Parkinson’s disease. However, so far, the impact of PPN DBS is very variable. We are refining the clinical method of PPN DBS to improve its effectiveness – by identifying which patients are likely to respond and the ideal location to implant electrodes.

Collaborators: Bionics Institute, Australia Pacific Centre of Neuromodulation, Australian Catholic University, University of Oxford

Funders: NHMRC, Brain Foundation, ACU Faculty grant

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